منابع مشابه
Synaptic plasticity in early aging.
Studies of how aging affects brain plasticity have largely focused on old animals. However, deterioration of memory begins well in advance of old age in animals, including humans; the present review is concerned with the possibility that changes in synaptic plasticity, as found in the long-term potentiation (LTP) effect, are responsible for this. Recent results indicate that impairments to LTP ...
متن کاملAging and Synaptic Plasticity: A Review
Aging affects all systems, but the brain seems to be particularly vulnerable to the action of negative, age-dependent factors. A gradual loss of memory functions is one of the earliest and most widespread consequences of brain aging. The causes for such impairment are still unclear. Long-term potentiation (LTP) is one form of neural plasticity, which has been proposed as the cellular correlate ...
متن کاملsynaptic neuronal plasticity
context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
متن کاملP7: The Role of Aquaporins in Synaptic Plasticity and Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملEpigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging.
Aging-related cognitive declines are well documented in humans and animal models. Yet the synaptic and molecular mechanisms responsible for cognitive aging are not well understood. Here we demonstrated age-dependent deficits in long-term synaptic plasticity and loss of dendritic spines in the hippocampus of aged Fisher 344 rats, which were closely associated with reduced histone acetylation, up...
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ژورنال
عنوان ژورنال: Ageing Research Reviews
سال: 2006
ISSN: 1568-1637
DOI: 10.1016/j.arr.2006.03.008